TROAP

TROAP
Identifiers
Aliases	TROAP, TASTIN, trophinin associated protein
External IDs	OMIM: 603872; MGI: 1925983; HomoloGene: 28697; GeneCards: TROAP; OMA:TROAP - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.12 Start 49,323,236 bp[1] End 49,331,731 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 F1 Start 98,972,456 bp[2] End 98,981,290 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte ventricular zone ganglionic eminence left testis right testis gonad mucosa of transverse colon bone marrow bone marrow cell Top expressed in zygote yolk sac secondary oocyte ventricular zone genital tubercle tail of embryo embryo embryo spermatocyte epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm Biological process cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10024 78733 Ensembl ENSG00000135451 ENSMUSG00000032783 UniProt Q12815 B7ZNG4 RefSeq (mRNA) NM_001100620 NM_001278324 NM_005480 NM_001162506 NM_030159 RefSeq (protein) NP_001094090 NP_001265253 NP_005471 NP_001155978 NP_084435 Location (UCSC) Chr 12: 49.32 – 49.33 Mb Chr 15: 98.97 – 98.98 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Trophinin-associated protein is a protein that in humans is encoded by the TROAP gene.^[5][6]

Interactions

TROAP has been shown to interact with BYSL.^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000135451 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032783 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fukuda MN, Sato T, Nakayama J, Klier G, Mikami M, Aoki D, Nozawa S (Jun 1995). "Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation". Genes Dev. 9 (10): 1199–210. doi:10.1101/gad.9.10.1199. PMID 7758945.
6. "Entrez Gene: TROAP trophinin associated protein (tastin)".
7. Suzuki N, Zara J, Sato T, Ong E, Bakhiet N, Oshima RG, Watson KL, Fukuda MN (Apr 1998). "A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 95 (9): 5027–32. Bibcode:1998PNAS...95.5027S. doi:10.1073/pnas.95.9.5027. PMC 20207. PMID 9560222.

Further reading

• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN (2002). "Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton". Biochem. J. 364 (Pt 3): 669–77. doi:10.1042/BJ20011836. PMC 1222615. PMID 12049630.
• Suzuki N, Nakayama J, Shih IM, Aoki D, Nozawa S, Fukuda MN (1999). "Expression of trophinin, tastin, and bystin by trophoblast and endometrial cells in human placenta". Biol. Reprod. 60 (3): 621–7. doi:10.1095/biolreprod60.3.621. PMID 10026108.
• Suzuki N, Zara J, Sato T, Ong E, Bakhiet N, Oshima RG, Watson KL, Fukuda MN (1998). "A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 95 (9): 5027–32. Bibcode:1998PNAS...95.5027S. doi:10.1073/pnas.95.9.5027. PMC 20207. PMID 9560222.

External links

• TROAP human gene location in the UCSC Genome Browser.
• TROAP human gene details in the UCSC Genome Browser.