G-3 (drug)

G-3

Clinical data
Other names	G3; Ganesha-3; GANESHA-3; 3C-G-3; 3,4-Trimethylene-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-(trimethylene)amphetamine; DOG-3
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Pharmacokinetic data
Duration of action	8–12 hours[1]
Identifiers
IUPAC name 1-(4,7-dimethoxy-2,3-dihydro-1H-inden-5-yl)propan-2-amine
CAS Number	207740-36-1
PubChem CID	44350047
ChemSpider	23206457
ChEMBL	ChEMBL124570
Chemical and physical data
Formula	C14H21NO2
Molar mass	235.327 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC(=C2CCCC2=C1OC)OC)N
InChI InChI=1S/C14H21NO2/c1-9(15)7-10-8-13(16-2)11-5-4-6-12(11)14(10)17-3/h8-9H,4-7,15H2,1-3H3 Key:GLFZOKOHBIKEKN-UHFFFAOYSA-N

G-3, also known as 3,4-trimethylene-2,5-dimethoxyamphetamine, is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.^[1][2][3] It is one of several homologues of Ganesha (G).^[1][2][3] In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists G-3's dose as 12 to 18 mg orally and its duration as 8 to 12 hours.^[1][2][3] The effects of G-3 were reported to include closed-eye imagery, no visuals, fantasy, warmth, mellowness, no body disturbance to hints of body discomfort, and "some suggestions of neurological sensitivity".^[1] Music was described as not that exciting and it was felt that there could be easy eroticism but there was no push for it.^[1] The drug was rated a "plus-three" on the Shulgin Rating Scale despite there "not [being] much of anything" in one report.^[1] The chemical synthesis of G-3 has been described.^[1] G-3 was first described in the literature by Shulgin in PiHKAL in 1991.^[1]

See also

• Ganesha (psychedelics)
• DOx (psychedelics)
• 2C-G-3
• DMMDA

References

1. Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. https://erowid.org/library/books_online/pihkal/pihkal082.shtml
2. Jacob P, Shulgin AT (1994). "Structure-Activity Relationships of the Classic Hallucinogens and Their Analogs". In Lin GC, Glennon RA (eds.). Hallucinogens: An Update (PDF). National Institute on Drug Abuse Research Monograph Series. Vol. 146. National Institute on Drug Abuse. pp. 74–91. PMID 8742795. Archived from the original on 13 July 2025.
3. Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.

External links

• G-3 - Isomer Design
• G-3 - PiHKAL - Erowid
• G-3 - PiHKAL - Isomer Design