GPR157

GPR157
Identifiers
Aliases	GPR157, G protein-coupled receptor 157
External IDs	MGI: 2442046; HomoloGene: 18573; GeneCards: GPR157; OMA:GPR157 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.22 Start 9,100,305 bp[1] End 9,129,102 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 E2 Start 150,171,822 bp[2] End 150,190,384 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in vastus lateralis muscle skin of arm gums gingival epithelium Skeletal muscle tissue of biceps brachii oral cavity Skeletal muscle tissue of rectus abdominis skin of thigh tibialis anterior muscle nasal epithelium Top expressed in muscle of thigh quadriceps femoris muscle muscle tissue skeletal muscle tissue granulocyte lip heart zone of skin yolk sac esophagus More reference expression data BioGPS n/a
Gene ontology Molecular function transmembrane signaling receptor activity signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane ciliary membrane cell projection Biological process cell surface receptor signaling pathway signal transduction G protein-coupled receptor signaling pathway circadian behavior positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway radial glial cell differentiation multicellular organism development cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80045 269604 Ensembl ENSG00000180758 ENSMUSG00000047875 UniProt Q5UAW9 Q8C206 RefSeq (mRNA) NM_024980 NM_177366 RefSeq (protein) NP_079256 NP_796340 Location (UCSC) Chr 1: 9.1 – 9.13 Mb Chr 4: 150.17 – 150.19 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 157 is a protein that in humans is encoded by the GPR157 gene.^[5][6]

References

1. GRCh38: Ensembl release 89: ENSG00000180758 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047875 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
6. "Entrez Gene: GPR157 G protein-coupled receptor 157".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Takeo Y, Kurabayashi N, Nguyen MD, Sanada K, et al. (2016). "The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway". Scientific Reports. 6: 25180–92. Bibcode:2016NatSR...625180T. doi:10.1038/srep25180. PMC 4855140. PMID 27142930.