Carnitine O-palmitoyltransferase

Choline/Carnitine o-acyltransferase
Structure of carnitine acetyltransferase.[1]
Identifiers
Symbol	Carn_acyltransf
Pfam	PF00755
Pfam clan	CL0149
InterPro	IPR000542
PROSITE	PDOC00402
SCOP2	1ndi / SCOPe / SUPFAM
OPM superfamily	83
OPM protein	2h3u
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase) is a mitochondrial transferase enzyme (EC 2.3.1.21) involved in the metabolism of palmitoylcarnitine into palmitoyl-CoA. A related transferase is carnitine acyltransferase.

Molecules

• 
  Palmitoylcarnitine
• 
  Palmitoyl CoA

Human forms

There are four different forms of CPT in humans:

• CPT1A – associated with Carnitine palmitoyltransferase I deficiency
• CPT1B
• CPT1C
• CPT2 – associated with carnitine palmitoyltransferase II deficiency

See also

• Fatty acid degradation § Transport into the mitochondrial matrix

References

1. Jogl G, Tong L (January 2003). "Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport". Cell. 112 (1): 113–22. doi:10.1016/S0092-8674(02)01228-X. PMID 12526798.

External links

• PDOC00402 – Acyltransferases ChoActase / COT / CPT family in PROSITE
• Choline/Carnitine o-acyltransferase family^{[permanent dead link]} in Pfam
• UMich Orientation of Proteins in Membranes protein/pdbid-2h4t
• Carnitine+O-Palmitoyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)