Iris (drug)

IRIS

Clinical data
Other names	IRIS; 2-Methoxy-5-ethoxy-4-methylamphetamine; DOM-5ETO; DOM-5EtO
Routes of administration	Oral[1]
ATC code	None
Pharmacokinetic data
Duration of action	Unknown[1]
Identifiers
IUPAC name 1-(5-ethoxy-2-methoxy-4-methylphenyl)propan-2-amine
CAS Number	952016-59-0^Y
PubChem CID	44719575
ChemSpider	21106327^Y
UNII	V3WW7XL92Q
CompTox Dashboard (EPA)	DTXSID20660367
Chemical and physical data
Formula	C13H21NO2
Molar mass	223.316 g·mol^−1
3D model (JSmol)	Interactive image
SMILES COc1cc(C)c(cc1CC(C)N)OCC
InChI InChI=1S/C13H21NO2/c1-5-16-12-8-11(7-10(3)14)13(15-4)6-9(12)2/h6,8,10H,5,7,14H2,1-4H3^Y Key:IPJRCKIREPMKNE-UHFFFAOYSA-N^Y
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Iris, also known as 2-methoxy-5-ethoxy-4-methylamphetamine or as DOM-5ETO, is a drug and a substituted amphetamine.^[1][2][3] It is also the 5-ethoxy analogue of DOM.^[1][2][3] The drug was first synthesized by Alexander Shulgin.^[1] In his book PiHKAL (Phenethylamines I Have Known and Loved), the minimum dose is listed as 9 mg orally and the duration as unknown.^[1][2] Iris produces few to no effects.^[1][2] Very little data exists about the pharmacological properties, metabolism, and toxicity of IRIS.^[1] The drug is one of Shulgin's "ten classic ladies", a series of methylated DOM derivatives.^[1][3]

See also

• DOx (psychedelics)
• TWEETIO (psychedelics)
• Beatrice (N-methyl-DOM)
• Florence (DOM-2ETO)

References

1. Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. IRIS entry
2. Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
3. Ger A, Ger D. "Triple Goddess of the Night". British Neuroscience Association Bulletin. 63: 28–30.

External links

• DOM-5ETO (IRIS) - Isomer Design