3,4-Methylenedioxy-N-methylphentermine

Pharmaceutical compound
MDMP
Clinical data
Other namesMDMP; MDMPH; 3,4-Methylenedioxy-α,α,N-trimethylphenethylamine
Routes of
administration		Oral[1]
ATC code
  • None
Pharmacokinetic data
Duration of action"Perhaps 6 hours"[1]
Identifiers
  • 1-(2H-1,3-benzodioxol-5-yl)-N,2-dimethylpropan-2-amine
CAS Number
  • 81262-69-3
PubChem CID
  • 44366836
ChemSpider
  • 21106335
UNII
  • P556669V7S
ChEMBL
  • ChEMBL347779
CompTox Dashboard (EPA)
  • DTXSID10658475
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(C)(NC)Cc1ccc2OCOc2c1
  • InChI=1S/C12H17NO2/c1-12(2,13-3)7-9-4-5-10-11(6-9)15-8-14-10/h4-6,13H,7-8H2,1-3H3
  • Key:CRFWCCGPRXKZSM-UHFFFAOYSA-N

3,4-Methylenedioxy-N-methylphentermine (MDMP or MDMPH), also known as 3,4-methylenedioxy-α,α,N-trimethylphenethylamine, is a lesser-known drug.[1]

Use and effects

MDMP was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the minimum dose is listed as 110 mg, and the duration is listed as approximately 6 hours.[1] MDMP produces few to no effects, and is slightly similar to MDMA.[1]

Pharmacology

Pharmacodynamics

MDMP failed to act as a serotonin releasing agent in rat brain synaptosomes in vitro.[2][3][4]

Society and culture

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.[5]

See also

References

  1. ^ a b c d e f Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. MDMP entry
  2. ^ Nichols DE, Oberlender R (1989). "Structure-activity relationships of MDMA-like substances" (PDF). NIDA Research Monograph. 94: 1–29. PMID 2575223. Archived from the original (PDF) on May 11, 2023.
  3. ^ Nichols DF, Oberlender R (1990). "Structure-Activity Relationships of MDMA and Related Compounds: A New Class of Psychoactive Agents?". Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA. Topics in the Neurosciences. Vol. 9. Boston, MA: Springer US. pp. 105–131. doi:10.1007/978-1-4613-1485-1_7. ISBN 978-1-4612-8799-5. PMID 1979214. Retrieved 19 November 2025.
  4. ^ Nichols DE, Lloyd DH, Hoffman AJ, Nichols MB, Yim GK (May 1982). "Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes". Journal of Medicinal Chemistry. 25 (5): 530–535. doi:10.1021/jm00347a010. PMID 7086839.
  5. ^ "UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Archived from the original on 22 October 2017. Retrieved 12 March 2014.
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