Professor Janice M. Marshall PhD DSc, FMedSci, FRBS, FBPhS(Hon) was a British physiologist, best known for her work on blood vessels and their autonomic regulation. She was the Bowman Professor of Physiology at the University of Birmingham, with a particular interest in the cardiovascular system
Biography
Roles within the University of Birmingham have included including Head of the Division of Medical Sciences, and she was the first Director of Education for the College of Medical & Dental Sciences (now the College of Medicine and Health).[1]
Marshall was elected as a fellow of the Academy of Medical Sciences in 1999.[2]
In 2024 she chaired the International Society for Autonomic Neuroscience congress in Birmingham.[3][4]
She died on 21 February 2025 following a cardiac arrest.
Work
Marshall led a group that significantly added to our understanding of the skeletal muscle blood flow response to exercise, mechanisms contributing to vasospasm in Primary Raynaud’s and Sickle Cell Disease, and the sex and ethnicity differences in cardiovascular control which may contribute to differential risk of cardiovascular disease and potential benefit of dietary and exercise interventions.
Marshall's most influential work relates to:
- the autonomic regulation of blood flow to muscle[5] and the gut.[6]
- hypoxia-induced vasodilation,[7] and the concept of functional sympatholysis, where the release of local vasodilators blocks the vasoconstrictive response of sympathetic nerves.[8]
- the pathophysiology of Raynaud's disease[9]
Her most recent work focusses on cardiovascular regulation during exercise, hypoxia, mental stress, ethnicity and early markers of cardiovascular disease.[10]
References
- ^ "Professor Janice Marshall". University of Birmingham. Retrieved 24 February 2025.
- ^ "Professor Janice Marshall". acmedsci.ac.uk.
- ^ "ISAN 2024" (PDF). Physiology News. 133: 37. 2024.
- ^ "ISAN 2024 Homepage - ISAN 2024". ISAN 2024 Homepage. Retrieved 24 February 2025.
- ^ Marshall, Janice M. (November 1982). "The influence of the sympathetic nervous system on individual vessels of the microcirculation of skeletal muscle of the rat". The Journal of Physiology. 332 (1): 169–186. doi:10.1113/jphysiol.1982.sp014408. PMC 1197393.
- ^ Furness, J. B.; Marshall, Janice M. (May 1974). "Correlation of the directly observed responses of mesenteric vessels of the rat to nerve stimulation and noradrenaline with the distribution of adrenergic nerves". The Journal of Physiology. 239 (1): 75–88. doi:10.1113/jphysiol.1974.sp010556. PMC 1330938.
- ^ Ray, Clare J.; Abbas, Mark R.; Coney, Andrew M.; Marshall, Janice M. (October 2002). "Interactions of adenosine, prostaglandins and nitric oxide in hypoxia‐induced vasodilatation: in vivo and in vitro studies". The Journal of Physiology. 544 (1): 195–209. doi:10.1113/jphysiol.2002.023440. PMC 2290577.
- ^ Marshall, Janice M. (December 2015). "Interactions between local dilator and sympathetic vasoconstrictor influences in skeletal muscle in acute and chronic hypoxia". Experimental Physiology. 100 (12): 1400–1411. doi:10.1113/EP085139.
- ^ Cooke, John P; Marshall, Janice M (November 2005). "Mechanisms of Raynaud's disease". Vascular Medicine. 10 (4): 293–307. doi:10.1191/1358863x05vm639ra.
- ^ "Professor Janice Marshall". acmedsci.ac.uk. Retrieved 24 February 2025.
External links
- Official website
