Quinethazone

Quinethazone

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Oral
ATC code	C03BA02 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline- 6-sulfonamide
CAS Number	73-49-4^Y
PubChem CID	6307
IUPHAR/BPS	7289
DrugBank	DB01325^Y
ChemSpider	6068^Y
UNII	455E0S048W
KEGG	D00461^Y
ChEMBL	ChEMBL1532^Y
CompTox Dashboard (EPA)	DTXSID9023548
ECHA InfoCard	100.000.729
Chemical and physical data
Formula	C10H12ClN3O3S
Molar mass	289.73 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c2c(Cl)cc1c(C(=O)NC(N1)CC)c2)N
InChI InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)^Y Key:AGMMTXLNIQSRCG-UHFFFAOYSA-N^Y
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Quinethazone (INN, brand name Hydromox) is a thiazide-like diuretic used to treat hypertension.^[1] Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

References

1. Sandler G (August 1964). "Quinethazone, a new oral diuretic". British Medical Journal. 2 (5404): 288–92. doi:10.1136/bmj.2.5404.288. PMC 1815620. PMID 14160213.