Protionamide

Protionamide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J04AD01 (WHO) ;
Identifiers
	IUPAC name 2-propylpyridine-4-carbothioamide;
CAS Number	14222-60-7 Y;
PubChem CID	666418;
DrugBank	DB12667 Y;
ChemSpider	579891 N;
UNII	76YOO33643;
CompTox Dashboard (EPA)	DTXSID7045940 ;
ECHA InfoCard	100.034.615
Chemical and physical data
Formula	C9H12N2S
Molar mass	180.27 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCc1cc(ccn1)C(=S)N;
	InChI InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) N; Key:VRDIULHPQTYCLN-UHFFFAOYSA-N N;
	NY (what is this?) (verify)

Chemical compound

Pharmaceutical compound

Protionamide (or prothionamide) is a medication used in the treatment of tuberculosis and leprosy.^[1]^[2]

References

^ Wang F, Langley R, Gulten G, Dover LG, Besra GS, Jacobs WR, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". The Journal of Experimental Medicine. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
^ Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". The American Journal of Tropical Medicine and Hygiene. 74 (3): 457–61. doi:10.4269/ajtmh.2006.74.457. PMID 16525107.
^ World Health Organization (2025). The selection and use of essential medicines, 2025: WHO Model List of Essential Medicines, 24th list. Geneva: World Health Organization. doi:10.2471/B09474. hdl:10665/382243.

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