2-Oxoadipic acid

2-Oxoadipic acid^[1]

Skeletal formula of α-ketoadipic acid Ball and stick model of α-ketoadipic acid
Names
Preferred IUPAC name 2-Oxohexanedioic acid[2]
Other names α-Ketoadipic acid2-Ketoadipic acidα-Oxoadipic acid
Identifiers
CAS Number	3184-35-8^Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:15753^Y
ChemSpider	70^Y
ECHA InfoCard	100.164.320
IUPHAR/BPS	4657
KEGG	C00322^Y
MeSH	Alpha-ketoadipic+acid
PubChemCID	71
UNII	BB72FKL1M2^Y
CompTox Dashboard(EPA)	DTXSID20185702
InChI InChI=1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)^Y Key: FGSBNBBHOZHUBO-UHFFFAOYSA-N^Y InChI=1/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11) Key: FGSBNBBHOZHUBO-UHFFFAOYAU
SMILES C(CC(=O)C(=O)O)CC(=O)O O=C(C(=O)O)CCCC(=O)O
Properties
Chemical formula	C6H8O5
Molar mass	160.125 g·mol^−1
Density	1.4 g cm^−3
Melting point	125 °C (257 °F; 398 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

2-Oxoadipic acid, also known as α-ketoadipic acid, is an intermediate in the metabolism of lysine and tryptophan.^[3][4] The conjugate base and carboxylate is 2-oxoadipate or α-ketoadipate, which is the biochemically relevant form.

See also

• Homoisocitrate dehydrogenase
• 2-oxoadipate dehydrogenase complex (OADHC)

References

1. 2-oxoadipate - Compound Summary, PubChem.
2. "Alpha-ketoadipic acid". The PubChem Project. National Center for Biotechnology Information.
3. Voet, Donald; Voet, Judith G. (2011). Biochemistry (4th ed.). Hoboken, NJ: Wiley. pp. 1040–1043. ISBN 978-0-470-57095-1.
4. Dobrota, Dušan (2016). Lekárska biochémia [Medical biochemistry] (in Slovak) (2nd ed.). Martin: Osveta. pp. 329–330, 335–337. ISBN 978-80-8063-444-5.