Carbazole alkaloids

The carbazole alkaloids are natural products of the indole alkaloid type, derived from carbazole.^[1]

Occurrence

Carbazole alkaloids with unsubstituted benzene rings occur rarely. Olivacin has been found in the bark of Aspidosperma olivaceum and ellipticin in Ochrosia elliptica.^[2] Some carbazole alkaloids, especially glybomin B, have been isolated from Glycosmis pentaphylla.^[3]

Representatives

Representatives include, among others, glycozoline, olivacine and ellipticin^[2] and further glybomine B.^[3]

Glycozoline
Olivacine
Ellipticin
Glybomine B

Properties

Carbazole alkaloids have cytotoxic and antifungal properties. Furthermore, they have detrimental effects against HIV viruses and tumor cells.^[3] Olivacin has fluorescent properties.^[2]

References

^Entry on carbazole alkaloids. In: Römpp Online. Georg Thieme Verlag, accessed May 31, 2020.
^ ^a ^b ^cEberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, p. 49, ISBN 978-3-519-03542-8
^ ^a ^b ^cG. Yang, Y. Wu, Y. Chen (2012), "Alkaloids from the Stems of Glycosmis pentaphylla", Helvetica Chimica Acta, vol. 95, no. 8, pp. 1449–1454, doi:10.1002/hlca.201200027{{citation}}: CS1 maint: multiple names: authors list (link)

External links

[Römpp-1] Entry on carbazole alkaloids. In: Römpp Online. Georg Thieme Verlag, accessed May 31, 2020.

[Alkaloids-2] Eberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, p. 49, ISBN 978-3-519-03542-8

[A-3] G. Yang, Y. Wu, Y. Chen (2012), "Alkaloids from the Stems of Glycosmis pentaphylla", Helvetica Chimica Acta, vol. 95, no. 8, pp. 1449–1454, doi:10.1002/hlca.201200027{{citation}}: CS1 maint: multiple names: authors list (link)

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