SLC2A11

SLC2A11
Identifiers
Aliases	SLC2A11, GLUT10, GLUT11, solute carrier family 2 member 11
External IDs	OMIM: 610367; HomoloGene: 57126; GeneCards: SLC2A11; OMA:SLC2A11 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.23 Start 23,856,703 bp[1] End 23,886,312 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum sural nerve apex of heart pituitary gland body of pancreas nucleus accumbens anterior pituitary left ventricle hypothalamus human kidney n/a More reference expression data BioGPS n/a
Gene ontology Molecular function transporter activity transmembrane transporter activity sugar transmembrane transporter activity Cellular component integral component of membrane cell junction plasma membrane membrane nucleus Biological process carbohydrate transport transmembrane transport hexose transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 66035 n/a Ensembl ENSG00000275744 ENSG00000133460 n/a UniProt Q9BYW1 n/a RefSeq (mRNA) NM_001024938 NM_001024939 NM_001282864 NM_030807 n/a RefSeq (protein) NP_001020109 NP_001020110 NP_001269793 NP_110434 n/a Location (UCSC) Chr 22: 23.86 – 23.89 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) also known as glucose transporter type 10/11 (GLUT-10/11) is a protein that in humans is encoded by the SLC2A11 gene.^[3]

SLC2A11 belongs to a family of plasma membrane proteins that mediate transport of sugars across the membrane by facilitative diffusion.^[3][4]

References

1. ENSG00000133460 GRCh38: Ensembl release 89: ENSG00000275744, ENSG00000133460 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 11".
4. Sasaki T, Minoshima S, Shiohama A, Shintani A, Shimizu A, Asakawa S, Kawasaki K, Shimizu N (December 2001). "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants". Biochemical and Biophysical Research Communications. 289 (5): 1218–24. doi:10.1006/bbrc.2001.6101. PMID 11741323.

Further reading

• Doege H, Bocianski A, Scheepers A, Axer H, Eckel J, Joost HG, Schürmann A (October 2001). "Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle". The Biochemical Journal. 359 (Pt 2): 443–9. doi:10.1042/0264-6021:3590443. PMC 1222165. PMID 11583593.
• Wu X, Li W, Sharma V, Godzik A, Freeze HH (May 2002). "Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues". Molecular Genetics and Metabolism. 76 (1): 37–45. doi:10.1016/s1096-7192(02)00018-5. PMID 12175779.
• Scheepers A, Schmidt S, Manolescu A, Cheeseman CI, Bell A, Zahn C, Joost HG, Schürmann A (2005). "Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue". Molecular Membrane Biology. 22 (4): 339–51. doi:10.1080/09687860500166143. PMID 16154905. S2CID 40473467.
• Manolescu AR, Augustin R, Moley K, Cheeseman C (2007). "A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity". Molecular Membrane Biology. 24 (5–6): 455–63. doi:10.1080/09687680701298143. PMID 17710649. S2CID 35331716.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.