The following highways are numbered 159:
 | This list is incomplete; you can help by adding missing items. (August 2008) |
Canada
Prince Edward Island Route 159 (Peter Road)- Quebec Route 159
Costa Rica
Japan
United Kingdom
- A159 road
- B159 road
United States
- U.S. Route 159
- Alabama State Route 159
- Arkansas Highway 159
- California State Route 159 (former)
- Colorado State Highway 159
- Connecticut Route 159
- Florida State Road 159
- Georgia State Route 159
- Illinois Route 159
- Indiana State Road 159
- Kentucky Route 159
- Louisiana Highway 159
- Maine State Route 159
- Maryland Route 159
- Massachusetts Route 159
- Nevada State Route 159
- New Jersey Route 159
- New Mexico State Road 159
- New York State Route 159
- North Carolina Highway 159
- Ohio State Route 159
- Pennsylvania Route 159 (former)
- Tennessee State Route 159
- Texas State Highway 159
- Utah State Route 159
- Virginia State Route 159
- Wisconsin Highway 159
- Wyoming Highway 159
- Territories
| Preceded by 158 |
Lists of highways 159 |
Succeeded by 160 |
