NCAPD3

NCAPD3
Identifiers
Aliases	NCAPD3, CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6, non-SMC condensin II complex subunit D3, MCPH22
External IDs	OMIM: 609276; MGI: 2142989; HomoloGene: 41021; GeneCards: NCAPD3; OMA:NCAPD3 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q25 Start 134,150,113 bp[1] End 134,225,504 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 26,941,471 bp[2] End 27,006,611 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve secondary oocyte ventricular zone gonad prostate ganglionic eminence testicle stromal cell of endometrium right lobe of liver left testis Top expressed in hand Gonadal ridge Paneth cell primary oocyte thymus dermis human fetus superior cervical ganglion neural layer of retina abdominal wall More reference expression data BioGPS More reference expression data
Gene ontology Molecular function methylated histone binding chromatin binding protein binding histone binding Cellular component membrane nucleus condensed chromosome, centromeric region nucleoplasm Biological process mitotic chromosome condensation chromosome separation cell division cell cycle chromosome condensation meiotic chromosome condensation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23310 78658 Ensembl ENSG00000151503 ENSMUSG00000035024 UniProt P42695 Q6ZQK0 RefSeq (mRNA) NM_015261 NM_001372065 NM_001372068 NM_001372069 NM_001372070 NM_178113 NM_001382847 RefSeq (protein) NP_056076 NP_001358994 NP_001358997 NP_001358998 NP_001358999 NP_835214 NP_001369776 Location (UCSC) Chr 11: 134.15 – 134.23 Mb Chr 9: 26.94 – 27.01 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene.^[5][6][7][8] CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References

1. GRCh38: Ensembl release 89: ENSG00000151503 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035024 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (December 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 1 (5): 223–229. doi:10.1093/dnares/1.5.223. PMID 7584044.
6. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (June 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
7. Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–121. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007. S2CID 18811084.
8. "NCAPD3 non-SMC condensin II complex, subunit D3". National Center for Biotechnology Information. Retrieved June 10, 2012.

Further reading

• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.