Nafadotride

Nafadotride
Names
	IUPAC name N-{[(2S)-1-butylpyrrolidin-2-yl]methyl}-4-cyano-1-methoxy-2-naphthamide
Identifiers
CAS Number	149649-22-9 Y;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:64191;
ChEMBL	ChEMBL286252 N;
ChemSpider	2652798;
IUPHAR/BPS	44;
MeSH	Nafadotride
PubChem CID	3408722;
UNII	JP25MZ26IQ Y;
CompTox Dashboard (EPA)	DTXSID1042603 ;
	InChI InChI=1S/C22H27N3O2/c1-3-4-11-25-12-7-8-17(25)15-24-22(26)20-13-16(14-23)18-9-5-6-10-19(18)21(20)27-2/h5-6,9-10,13,17H,3-4,7-8,11-12,15H2,1-2H3,(H,24,26) Key: IDZASIQMRGPBCQ-UHFFFAOYSA-N;
	SMILES CCCCN1CCCC1CNC(=O)C2=C(C3=CC=CC=C3C(=C2)C#N)OC;
Properties
Chemical formula	C22H27N3O2
Molar mass	365.477 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Nervous system drug

Chemical compound

Nafadotride is a dopamine antagonist with some selectivity for the D₃ subtype (9.6-fold preference for D₃ over D₂).^[1]

References

^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.